Differential methylation of human LINE-1 retrotransposons in malignant cells

Hypomethylation distinguishes genes of some human cancers from their normal counterparts

Andrew P. Feinberg, Bert Vogelstein · Nature · 1983 · 2.4K citations

Medicine, Genetics, Molecular Genetics +13

Haemophilia A resulting from de novo insertion of L1 sequences represents a novel mechanism for mutation in man

Haig H. Kazazian, Corinne Wong, Hagop Youssoufian et al. · Nature · 1988 · 928 citations

Life Sciences, Genetics, Molecular Genetics +4

Hypomethylation of DNA from Benign and Malignant Human Colon Neoplasms

Susan Goelz, Bert Vogelstein, Stanley R. Hamilton et al. · Science · 1985 · 838 citations

Medicine, Molecular Biology, Oncology +16

Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization.

Anne Kallioniemi, Olli Kallioniemi, Jim Piper et al. · Proceedings of the National Academy of Sciences · 1994 · 748 citations

Life Sciences, Genetics, Oncology +17

Disruption of the APC gene by a retrotransposal insertion of L1 sequence in a colon cancer.

Yoshio Miki, Isamu Nishisho, Akira Horii et al. · PubMed · 1992 · 582 citations

Life Sciences, Genetics, Molecular Genetics +17