Concepedia

Synthesis and biological evaluation of 3-heteroaryloxy-4-phenyl-2(5H)-furanones as selective COX-2 inhibitors

Cheuk K. Lau, Christine Brideau, Chi Chung Chan, S. Charleson, Wanda Cromlish, Diane Ethier, Jacques Yves Gauthier, Robert J. Gordon, Jocelyne Guay, Stacia Kargman,

Bioorganic & Medicinal Chemistry Letters · 1999 · 29 citations · 11 references

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References

11

Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain.

Karen Seibert, Y Zhang, K. Leahy et al. · Proceedings of the National Academy of Sciences · 1994 · 1.6K citations

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NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions

Nobuko Futaki, Kensei Yoshikawa, Y Hamasaka et al. · General Pharmacology The Vascular System · 1993 · 347 citations

, , +13

Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX‐2 inhibitor

Denis Riendeau, M. David Percival, S. Boyce et al. · British Journal of Pharmacology · 1997 · 326 citations · Full text

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Pharmacology of a selective cyclooxygenase-2 inhibitor, L-745,337: a novel nonsteroidal anti-inflammatory agent with an ulcerogenic sparing effect in rat and nonhuman primate stomach.

Chi‐Chung Chan, S. Boyce, Christine Brideau et al. · Journal of Pharmacology and Experimental Therapeutics · 1995 · 314 citations

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A human whole blood assay for clinical evaluation of biochemical efficacy of cyclooxygenase inhibitors

Christine Brideau, Stacia Kargman, S. Liu et al. · Inflammation Research · 1996 · 281 citations

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