Peptide Borono Lectins (PBLs): A New Tool for Glycomics and Cancer Diagnostics

Abstract

Peptide borono lectins (PBLs) have been synthesized and shown to bind glycoproteins dependant on the glycoprotein and PBL structures. The binding is reversible and it has been demonstrated that both selective and cross-reactive PBLs can be identified. The potential utility of these PBLs as a cancer diagnostic has been demonstrated.