Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation

Huw D. Lewis, John Liddle, Jim Coote, +30

Nature Chemical Biology

Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis

Carmelo Carmona‐Rivera, Philip M. Carlucci, Erica Moore, +13

Science Immunology

Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor α target gene activation

Xuesen Zhang, Michael J. Bolt, Michael J. Guertin, +11

Proceedings of the National Academy of Sciences

Histone ModificationsMolecular RegulationEpigenetic ChangeMolecular BiologyGene Activity +18

Seeing Citrulline: Development of a Phenylglyoxal-Based Probe To Visualize Protein Citrullination

Kevin L. Bicker, Venkataraman Subramanian, Alexander A. Chumanevich, +2

Journal of the American Chemical Society

Chemical Proteomic Platform To Identify Citrullinated Proteins

Daniel M. Lewallen, Kevin L. Bicker, Venkataraman Subramanian, +7

ACS Chemical Biology

EngineeringMolecular BiologyProteomic TechnologyProtein FoldingLong Non-coding Rna +16

Peptide Borono Lectins (PBLs): A New Tool for Glycomics and Cancer Diagnostics

Yuejiao Zou, Dana L. Broughton, Kevin L. Bicker, +2

ChemBioChem

Cancer DiagnosticsNew ToolGlycobiologyMolecular BiologyChemical Biology +15

<scp>d</scp>-Amino Acid-Based Protein Arginine Deiminase Inhibitors: Synthesis, Pharmacokinetics, and in Cellulo Efficacy

Kevin L. Bicker, Lynne J. Anguish, Alexander A. Chumanevich, +9

ACS Medicinal Chemistry Letters

Medicinal ChemistryBiochemistryMedicineNatural SciencesAnti-cancer Agent +10

Boronic Acid Functionalized Peptidyl Synthetic Lectins: Combinatorial Library Design, Peptide Sequencing, and Selective Glycoprotein Recognition

Kevin L. Bicker, Jing Sun, John J. Lavigne, +1

ACS Combinatorial Science

Selective Glycoprotein RecognitionPeptide EngineeringAberrant GlycosylationGlycobiologyPeptide Sequencing +14

Synthetic lectin arrays for the detection and discrimination of cancer associated glycans and cell lines

Kevin L. Bicker, Jing Sun, Morgan Harrell, +4

Chemical Science

Aberrant GlycosylationGlycobiologyPathologyCancer BiologyTumor Biology +16

A FluoPol-ABPP PAD2 High-Throughput Screen Identifies the First Calcium Site Inhibitor Targeting the PADs

Daniel M. Lewallen, Kevin L. Bicker, Franck Madoux, +5

ACS Chemical Biology

Molecular BiologyTumor BiologyMolecular PharmacologyTranscriptional RegulationEnzyme Active Site +19