Activation of peroxisome proliferator‐activated receptor γ inhibits cell growth via apoptosis and arrest of the cell cycle in human colorectal cancer

Abstract

Our results showed that PPARgamma was expressed in HT-29 cells and PPARgamma activation could inhibit cell growth through inducing apoptosis and suppressing the cell cycle. PPARgamma may be considered as a new therapeutic target for colon cancer in humans.