Malignant Transformation of NIH3T3 Cells by Overexpression of Early Lymphocyte Activation Antigen CD98

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.3K citations · Full text

Life Sciences, Microbiology, Molecular Biology +10

Expression Cloning and Characterization of a Transporter for Large Neutral Amino Acids Activated by the Heavy Chain of 4F2 Antigen (CD98)

Yoshikatsu Kanai, Hiroko Segawa, Ken‐ichi Miyamoto et al. · Journal of Biological Chemistry · 1998 · 1.1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

An essential role for Rac in Ras transformation

Rongguo Qiu, Jing Chen, David H. Kirn et al. · Nature · 1995 · 885 citations

Medicine, Molecular Biology, Oncogenes +7

Ligand-specific activation of HER4/p180erbB4, a fourth member of the epidermal growth factor receptor family.

Gregory D. Plowman, Jean‐Michel Culouscou, Gena S. Whitney et al. · Proceedings of the National Academy of Sciences · 1993 · 718 citations

Life Sciences, Molecular Biology, Oncology +14

Activation of Rac1, RhoA, and Mitogen-Activated Protein Kinases Is Required for Ras Transformation

Roya Khosravi‐Far, Patricia A. Solski, Geoffrey Clark et al. · Molecular and Cellular Biology · 1995 · 676 citations · Full text

Medicine, Cell Biology, Molecular Biology +17