Concepedia

An assay combining high-performance liquid chromatography and mass spectrometry to measure DNA interstrand cross-linking efficiency in oligonucleotides of varying sequences

Mathangi Narayanaswamy, William J. Griffiths, Philip W. Howard, David E. Thurston

Analytical Biochemistry · 2007 · 25 citations · 21 references

DOI

Concepts

References

21

Design, Synthesis, and Evaluation of a Novel Pyrrolobenzodiazepine DNA-Interactive Agent with Highly Efficient Cross-Linking Ability and Potent Cytotoxicity

Stephen J. Gregson, Philip W. Howard, John A. Hartley et al. · Journal of Medicinal Chemistry · 2001 · 200 citations

, , +17

Determination of affinity, stoichiometry and sequence selectivity of minor groove binder complexes with double-stranded oligodeoxynucleotides by electrospray ionization mass spectrometry

Frédéric Rosu · Nucleic Acids Research · 2002 · 143 citations · Full text

, , +15

SJG-136 (NSC 694501), a Novel Rationally Designed DNA Minor Groove Interstrand Cross-Linking Agent with Potent and Broad Spectrum Antitumor Activity

John A. Hartley, Victoria J. Spanswick, Natalie Brooks et al. · Cancer Research · 2004 · 137 citations

, , +15

An agarose gel method for the determination of DNA interstrand crosslinking applicable to the measurement of the rate of total and “second-arm” crosslink reactions

John A. Hartley, Mark Berardini, Robert L. Souhami · Analytical Biochemistry · 1991 · 108 citations

, , +11

Observation of daunomycin and nogalamycin complexes with duplex DNA using electrospray ionisation mass spectrometry

Amit Kapur, Jennifer L. Beck, Margaret M. Sheil · Rapid Communications in Mass Spectrometry · 1999 · 102 citations

, , +14