Concepedia

Computer-aided drug design and ADMET predictions for identification and evaluation of novel potential farnesyltransferase inhibitors in cancer therapy

Carlos Henrique Tomich de Paula da Silva, Vinícius Barreto da Silva, Patrícia Franco Rodrigues, Fernanda C. Bononi, Carolina Gomes Benevenuto, Carlton A. Taft

Journal of Molecular Graphics and Modelling · 2009 · 33 citations · 29 references

DOI

Concepts

References

29

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Christopher A. Lipinski, Franco Lombardo, Beryl W. Dominy et al. · Advanced Drug Delivery Reviews · 1997 · 11.2K citations

, , +16

ras oncogenes in human cancer: a review.

Joyce Bos · PubMed · 1989 · 5.1K citations

, , +17

Improved protein–ligand docking using GOLD

Marcel L. Verdonk, Jason C. Cole, Michael J. Hartshorn et al. · Proteins Structure Function and Bioinformatics · 2003 · 3K citations · Full text

, , +17

A computational procedure for determining energetically favorable binding sites on biologically important macromolecules

P. J. Goodford · Journal of Medicinal Chemistry · 1985 · 2.6K citations

, , +17

Inhibition of purified p21 farnesyl:protein transferase by Cys-AAX tetrapeptides

Yuval Reiss, Joseph L. Goldstein, Miguel C. Seabra et al. · Cell · 1990 · 815 citations

, , +9