The significance of aberrant CHFR methylation for clinical response to microtubule inhibitors in gastric cancer

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

James G. Herman, Jeremy R. Graff, Sanna Myöhänen et al. · Proceedings of the National Academy of Sciences · 1996 · 5.7K citations

Life Sciences, Genetics, Molecular Biology +17

Inactivation of the DNA-Repair Gene<i>MGMT</i>and the Clinical Response of Gliomas to Alkylating Agents

Manel Esteller, Jesús García‐Foncillas, Esther Andion et al. · New England Journal of Medicine · 2000 · 2.2K citations · Full text

Medicine, Molecular Biology, Oncology +17

Aberrant methylation in gastric cancer associated with the CpG island methylator phenotype.

M Toyota, Nita Ahuja, Hiromu Suzuki et al. · PubMed · 1999 · 532 citations

Medicine, Molecular Biology, Oncology +17

Reversal of drug resistance in human tumor xenografts by 2'-deoxy-5-azacytidine-induced demethylation of the hMLH1 gene promoter.

Jane A. Plumb, Gordon Strathdee, Julieann Sludden et al. · PubMed · 2000 · 488 citations

Medicine, Cancer Biology, Oncology +16

Chfr defines a mitotic stress checkpoint that delays entry into metaphase

Daniel M. Scolnick, Thanos D. Halazonetis · Nature · 2000 · 376 citations

Life Sciences, Cell Biology, Molecular Biology +12