Concepedia

Age-dependent increase of prolyl-4-hydroxylase domain (PHD) 3 expression in human and mouse heart

Susanne Rohrbach, Andreas Simm, Reinhard Pregla, Corinna Franke, Dörthe M. Katschinski

Biogerontology · 2005 · 54 citations · 22 references

DOI

Concepts

References

22

Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O <sub>2</sub> -Regulated Prolyl Hydroxylation

Panu Jaakkola, David R. Mole, Ya‐Min Tian et al. · Science · 2001 · 5.5K citations

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

Patrick H. Maxwell, Michael S. Wiesener, Gin-Wen Chang et al. · Nature · 1999 · 5.2K citations

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HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O <sub>2</sub> Sensing

Mircea Ivan, Keiichi Kondo, Haifeng Yang et al. · Science · 2001 · 4.7K citations · Full text

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Asparagine Hydroxylation of the HIF Transactivation Domain: A Hypoxic Switch

David Lando, Daniel J. Peet, Dean A. Whelan et al. · Science · 2002 · 1.5K citations

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Independent function of two destruction domains in hypoxia‐inducible factor‐α chains activated by prolyl hydroxylation

Norma Masson, Carsten Willam, Patrick H. Maxwell et al. · The EMBO Journal · 2001 · 1K citations · Full text

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