Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen

Paul Lehmann, Thomas G. Forsthuber, Alexander Miller, +1

Nature

Cryptic DeterminantsAutoimmune DiseaseAutoantibody ProductionT-regulatory CellImmunology +7

IFN-Lambda (IFN-λ) Is Expressed in a Tissue-Dependent Fashion and Primarily Acts on Epithelial Cells In Vivo

Caroline Sommereyns, Sophie Paul, Peter Staeheli, +1

PLoS Pathogens

Primarily ActsImmunologyImmune RegulationViral PathogenesisInnate Immunity +24

Functional defect of regulatory CD4+CD25+ T cells in the thymus of patients with autoimmune myasthenia gravis

Sandrine Lécart, Philippe Dartevelle, Abdelhadi Saoudi, +1

Blood

Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire

Daniel H.D. Gray, Jakub Abramson, Christophe Benoıst, +1

The Journal of Experimental Medicine

ImmunologyCell DeathImmunologic MechanismCell ProliferationImmunotherapy +15

Selective contribution of IFN-α/β signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection

Kenya Honda, Shinya Sakaguchi, Chigusa Nakajima, +9

Proceedings of the National Academy of Sciences

Neutralization of interferon‐α/β–inducible genes and downstream effect in a phase I trial of an anti–interferon‐α monoclonal antibody in systemic lupus erythematosus

Yihong Yao, Laura K. Richman, Brandon W. Higgs, +8

Arthritis & Rheumatism

Association of CXCL13 and CCL21 expression with the progressive organization of lymphoid‐like structures in Sjögren's syndrome

Francesca Barone, Antonio Manzo, Mark C. Blades, +4

Arthritis & Rheumatism

Safety profile and clinical activity of sifalimumab, a fully human anti-interferon α monoclonal antibody, in systemic lupus erythematosus: a phase I, multicentre, double-blind randomised study

D. J. Wallace, M. Pétri, Kyriakos A. Kirou, +10

Annals of the Rheumatic Diseases

Autoantibodies against Type I Interferons as an Additional Diagnostic Criterion for Autoimmune Polyendocrine Syndrome Type I

Antonella Meloni, Maria Furcas, Filomena Cetani, +19

The Journal of Clinical Endocrinology & Metabolism

Anti-cytokine autoantibodies in autoimmunity: preponderance of neutralizing autoantibodies against interferon-alpha, interferon-omega and interleukin-12 in patients with thymoma and/or myasthenia gravis

Anthony Meager, Meenu Wadhwa, Paula Dilger, +4

Clinical & Experimental Immunology