Shinya Sakaguchi

Transcriptional reprogramming of mature CD4+ helper T cells generates distinct MHC class II–restricted cytotoxic T lymphocytes

Daniel Mucida, Mohammad Mushtaq Husain, Sawako Muroi et al. · Nature Immunology · 2013 · 379 citations

Life Sciences, Cell Biology, Immunology +17

Selective contribution of IFN-α/β signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection

Kenya Honda, Shinya Sakaguchi, Chigusa Nakajima et al. · Proceedings of the National Academy of Sciences · 2003 · 354 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Tyrosine Kinases Btk and Tec Regulate Osteoclast Differentiation by Linking RANK and ITAM Signals

Masahiro Shinohara, Takako Koga, Kazuo Okamoto et al. · Cell · 2008 · 321 citations · Full text

Medicine, Cell Biology, Bone Metabolism +15

Evidence for licensing of IFN-γ-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program

Hideo Negishi, Yasuyuki Fujita, Hideyuki Yanai et al. · Proceedings of the National Academy of Sciences · 2006 · 309 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Essential role of IRF-3 in lipopolysaccharide-induced interferon-β gene expression and endotoxin shock

Shinya Sakaguchi, Hideo Negishi, Masataka Asagiri et al. · Biochemical and Biophysical Research Communications · 2003 · 270 citations

Life Sciences, Immunology, Molecular Biology +16