Concepedia

Synthesis and SAR of 3,5-diamino-piperidine derivatives: Novel antibacterial translation inhibitors as aminoglycoside mimetics

Yuefen Zhou, V. Gregor, Benjamin K. Ayida, Geoffrey C. Winters, Zhongxiang Sun, Douglas E. Murphy, Greg Haley, Dwight Bailey, Jamie M. Froelich, Sarah Fish,

Bioorganic & Medicinal Chemistry Letters · 2006 · 128 citations · 12 references

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12

Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics

Andrew P. Carter, William Clemons, Ditlev E. Brodersen et al. · Nature · 2000 · 1.6K citations

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Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding

Boris François · Nucleic Acids Research · 2005 · 339 citations · Full text

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Antimicrobial Resistance in Gram-Positive Bacteria

Louis B. Rice · The American Journal of Medicine · 2006 · 273 citations

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The Molecular Basis for A‐Site Mutations Conferring Aminoglycoside Resistance: Relationship between Ribosomal Susceptibility and X‐ray Crystal Structures

Peter Pfister, Sven N. Hobbie, Quentin Vicens et al. · ChemBioChem · 2003 · 143 citations

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Molecular Recognition by Glycoside Pseudo Base Pairs and Triples in an Apramycin–RNA Complex

Qing Han, Qiang Zhao, Sarah Fish et al. · Angewandte Chemie International Edition · 2005 · 68 citations

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