Sven N. Hobbie

Genetic analysis of interactions with eukaryotic rRNA identify the mitoribosome as target in aminoglycoside ototoxicity

Sven N. Hobbie, Akshay Subramanian, Sarath K. Kalapala et al. · Proceedings of the National Academy of Sciences · 2008 · 182 citations · Full text

Mitochondrial Rrna, Molecular Biology, Molecular Genetics +18

The Molecular Basis for A‐Site Mutations Conferring Aminoglycoside Resistance: Relationship between Ribosomal Susceptibility and X‐ray Crystal Structures

Peter Pfister, Sven N. Hobbie, Quentin Vicens et al. · ChemBioChem · 2003 · 142 citations

X-ray Crystallography, Ribosomal Rna, Ribosomal Susceptibility +18

Mitochondrial deafness alleles confer misreading of the genetic code

Sven N. Hobbie, Christian M. Bruell, Akshay Subramanian et al. · Proceedings of the National Academy of Sciences · 2008 · 108 citations · Full text

Engineering, Ribosomal Rna, Genetics +20

<i>In vitro</i>activity of apramycin against multidrug-, carbapenem- and aminoglycoside-resistant Enterobacteriaceae and<i>Acinetobacter baumannii</i>

Mario Juhas, Emma Widlake, Jeanette Teo et al. · Journal of Antimicrobial Chemotherapy · 2018 · 107 citations · Full text

23S rRNA base pair 2057–2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A→G

Peter Pfister, Natascia Corti, Sven N. Hobbie et al. · Proceedings of the National Academy of Sciences · 2005 · 80 citations · Full text