Christian M. Bruell

Genetic analysis of interactions with eukaryotic rRNA identify the mitoribosome as target in aminoglycoside ototoxicity

Sven N. Hobbie, Akshay Subramanian, Sarath K. Kalapala et al. · Proceedings of the National Academy of Sciences · 2008 · 182 citations · Full text

Mitochondrial Rrna, Molecular Biology, Molecular Genetics +18

Mitochondrial deafness alleles confer misreading of the genetic code

Sven N. Hobbie, Christian M. Bruell, Akshay Subramanian et al. · Proceedings of the National Academy of Sciences · 2008 · 108 citations · Full text

Engineering, Ribosomal Rna, Genetics +20

Essential Mechanisms in the Catalysis of Peptide Bond Formation on the Ribosome

Malte Beringer, Christian M. Bruell, Liqun Xiong et al. · Journal of Biological Chemistry · 2005 · 90 citations · Full text

23S rRNA base pair 2057–2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A→G

Peter Pfister, Natascia Corti, Sven N. Hobbie et al. · Proceedings of the National Academy of Sciences · 2005 · 80 citations · Full text

Engineering the rRNA decoding site of eukaryotic cytosolic ribosomes in bacteria

Sven N. Hobbie, Sarath K. Kalapala, Akshay Subramanian et al. · Nucleic Acids Research · 2007 · 79 citations · Full text

Aminoglycoside Susceptibility, Hybrid Ribosomes, Biomolecular Structure Prediction +16