The Cloned Capsaicin Receptor Integrates Multiple Pain-Producing Stimuli

Makoto Tominaga, Michael J. Caterina, Annika B. Malmberg, +6

Neuron

Health SciencesPain MedicineMedicinePhysiologyNeuropathic Pain +7

The Cytolytic P _2Z Receptor for Extracellular ATP Identified as a P _2X Receptor (P2X ₇ )

Annmarie Surprenant, Eric Kawashima, R. Alan North, +1

Science

Pannexin‐1 mediates large pore formation and interleukin‐1β release by the ATP‐gated P2X7 receptor

Pablo Pelegrı́n, Annmarie Surprenant

The EMBO Journal

An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors

Susan M. Huang, Tiziana Bisogno, Marcello Trevisani, +12

Proceedings of the National Academy of Sciences

Synaptic TransmissionNeurotransmitterNeurotransmissionExperimental PharmacologySocial Sciences +16

TRP-PLIK, a Bifunctional Protein with Kinase and Ion Channel Activities

Loren W. Runnels, Lixia Yue, David E. Clapham

Science

Molecular BiologyCellular PhysiologyIon Channel ActivitiesSignaling PathwayCell Signaling +16

Acetylcholine Receptor Channel Structure Probed in Cysteine-Substitution Mutants

Myles H. Akabas, David A. Stauffer, Ming Xu, +1

Science

Lighting up the Senses: FM1-43 Loading of Sensory Cells through Nonselective Ion Channels

Jason R. Meyers, Richard B. MacDonald, Anne Duggan, +4

Journal of Neuroscience

NeurotransmitterFm1-43 LoadingNeurotransmissionCellular PhysiologySocial Sciences +21

Protein kinase C activation potentiates gating of the vanilloid receptor VR1 by capsaicin, protons, heat and anandamide

Vittorio Vellani, Sarah Mapplebeck, Andrea Moriondo, +2

The Journal of Physiology

Direct Phosphorylation of Capsaicin Receptor VR1 by Protein Kinase Cε and Identification of Two Target Serine Residues

Mitsuko Numazaki, Tomoko Tominaga, Hidenori Toyooka, +1

Journal of Biological Chemistry

Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers

Alexander M. Binshtok, Bruce P. Bean, Clifford J. Woolf

Nature

Trpv1-mediated EntryMolecular PhysiologyHealth SciencesPain MedicineMedicine +7