3-deazaneplanocin A: A new inhibitor of S-adenosylhomocysteine synthesis and its effects in human colon carcinoma cells

Studies on neplanocin a, new antitumor antibiotic. I. Producing organism, isolation and characterization.

Satoshi Yaginuma, Naoki Muto, Masatoshi Tsujino et al. · The Journal of Antibiotics · 1981 · 262 citations · Full text

Antiviral and antimetabolic activities of neplanocins

Erik De Clercq · Antimicrobial Agents and Chemotherapy · 1985 · 203 citations

Medicinal Chemistry, Medicine, Natural Sciences +14

Neplanocin A. A potent inhibitor of S-adenosylhomocysteine hydrolase and of vaccinia virus multiplication in mouse L929 cells.

R. T. BORCHARDT, B T Keller, Usha Patel-Thombre · Journal of Biological Chemistry · 1984 · 184 citations · Full text

Molecular Biology, Mouse L929 Cells, Antiviral Drug +17

Carbocyclic analog of 3-deazaadenosine: a novel antiviral agent using S-adenosylhomocysteine hydrolase as a pharmacological target

John A. Montgomery, S. J. CLAYTON, H. Jeanette Thomas et al. · Journal of Medicinal Chemistry · 1982 · 155 citations

S-adenosylhomocysteine Hydrolase, Medicinal Chemistry, Biochemistry +14

3-Deazaneplanocin: A new and potent inhibitor of S-adenosylhomocysteine hydrolase and its effects on human promyelocytic leukemia cell line HL-60

Robert I. Glazer, Kathleen D. Hartman, Marion C. Knode et al. · Biochemical and Biophysical Research Communications · 1986 · 153 citations

S-adenosylhomocysteine Hydrolase, Molecular Pharmacology, Medicinal Chemistry +8