Hydrolysis of enkephalin by cultured human endothelial cells and by purified peptidyl dipeptidase

Design of Specific Inhibitors of Angiotensin-Converting Enzyme: New Class of Orally Active Antihypertensive Agents

Miguel A. Ondetti, Bernard Rubin, David W. Cushman · Science · 1977 · 1.9K citations

Hypertension, Cardiovascular Pharmacology, Pharmacotherapy +16

Isolation of an endogenous compound from the brain with pharmacological properties similar to morphine

John Hughes · Brain Research · 1975 · 980 citations

Molecular Pharmacology, Psychoactive Drug, Pharmacological Study +13

A dipeptidyl carboxypeptidase that converts angiotensin I and inactivates bradykinin

Huanle Yang, E G Erdös, Yehuda Levin · Biochimica et Biophysica Acta (BBA) - Protein Structure · 1970 · 533 citations

Molecular Pharmacology, Dipeptidyl Carboxypeptidase, Biochemistry +6

Mode of deactivation of the enkephalins by rat and human plasma and rat brain homogenates

JEAN M. HAMBROOK, Barry A. Morgan, Michael J. Rance et al. · Nature · 1976 · 516 citations

Ependyma, Neurophysiology, Neuroanatomy +8

DISTRIBUTION AND PROPERTIES OF ANGIOTENSIN CONVERTING ENZYME OF RAT BRAIN

Hongdian Yang, Norton H. Neff · Journal of Neurochemistry · 1972 · 298 citations

Peptide Science, Experimental Pharmacology, Social Sciences +20