SWISS‐MODEL and the Swiss‐Pdb Viewer: An environment for comparative protein modeling

Nicolas Guex, Manuel C. Peitsch

Electrophoresis

Swiss‐pdb ViewerEngineeringStructural BioinformaticsBiomolecular Structure PredictionMolecular Biology +16

Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN

Vuk Stambolic, Akira Suzuki, José Luís de la Pompa, +7

Cell

Tumor BiologySignal TransductionSignaling PathwayCell RegulationMedicine +10

H ₂ O ₂ , a Necessary Evil for Cell Signaling

Sue Goo Rhee

Science

Lipid PeroxidationImmunologyMolecular BiologyCell DeathReactive Oxygen Species +22

Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells

Takeshi Fujiwara, Madhavi Bandi, Masayuki Nitta, +3

Nature

MedicineCytokinesis FailureCell DeathTumor SuppressorCancer Biology +2

Reversible Inactivation of the Tumor Suppressor PTEN by H2O2

Seung-Rock Lee, Kap‐Seok Yang, Jaeyul Kwon, +3

Journal of Biological Chemistry

Crystal Structure of the PTEN Tumor Suppressor

Jie‐Oh Lee, Haijuan Yang, Maria-Magdalena Georgescu, +6

Cell

Crystal StructureMolecular BiologyStructural BiologyTumor SuppressorMedicine +3

Thioredoxin-dependent peroxide reductase from yeast.

Ho Zoon Chae, Suk‐Jae Chung, Sue Goo Rhee

Journal of Biological Chemistry

Redox SignalingAldehyde DehydrogenaseAldo-keto ReductaseBiochemistryFungal Cell Biology +13

Specific protection against breast cancers by cyclin D1 ablation

Qunyan Yu, Yan Geng, Piotr Siciński

Nature

Cyclin D1 AblationBreast OncologyMedicinePathologyBreast Cancer +3

Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: Synergistic action of oncogenes in vivo

Eric Sinn, William J. Muller, Paul K. Pattengale, +3

Cell

Knockout MouseOncogenic AgentImmunologyGene RegulationSynergistic Action +6

Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression

Carola A. Neumann, Daniela S. Krause, Christopher V. Carman, +7

Nature

InflammationReductive StressEssential RoleRedox RegulatorMedicine +10