Concepedia

Transforming growth factor β1 is associated with angiogenesis, metastasis, and poor clinical outcome in prostate cancer

Pernilla Wikström, Pär Stattin, Ingela Franck-Lissbrant, Jan‐Erik Damber, Anders Bergh

The Prostate · 1998 · 311 citations · 44 references

DOI

Abstract

Overproduction of TGF-beta1 and loss of TGFbeta-RII expression are associated with poor clinical outcome in prostate cancer, and TGF-beta1 may promote tumor progression by stimulating angiogenesis and metastasis.

References

44

Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro.

Anita B. Roberts, Michael B. Sporn, Richard K. Assoian et al. · Proceedings of the National Academy of Sciences · 1986 · 2.9K citations · Full text

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Cloning of a TGF$beta; type I receptor that forms a heteromeric complex with the TGF$beta; type II receptor

Petra Franzèn · Cell · 1993 · 770 citations · Full text

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Vascular endothelial growth factor is induced in response to transforming growth factor-beta in fibroblastic and epithelial cells.

Liisa Pertovaara, Arja Kaipainen, Tuija Mustonen et al. · Journal of Biological Chemistry · 1994 · 692 citations · Full text

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Transforming growth factor beta 1-induced changes in cell migration, proliferation, and angiogenesis in the chicken chorioallantoic membrane.

Eun-Jin Yang, Harold L. Moses · The Journal of Cell Biology · 1990 · 468 citations · Full text

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Genetic changes in the transforming growth factor beta (TGF-beta) type II receptor gene in human gastric cancer cells: correlation with sensitivity to growth inhibition by TGF-beta.

Kwangsung Park, S J Kim, Yung‐Jue Bang et al. · Proceedings of the National Academy of Sciences · 1994 · 425 citations · Full text

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