Expression of the c-erbB-2 proto-oncogene product and nuclear DNA content in benign and malignant human breast parenchyma

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/<i>neu</i>Oncogene

Dennis J. Slamon, Gary M. Clark, Steven Wong et al. · Science · 1987 · 11.6K citations

Neu-Protein Overexpression in Breast Cancer

Marc J. van de Vijver, Johannes L. Peterse, Wolter J. Mooi et al. · New England Journal of Medicine · 1988 · 858 citations

A v-erbB-related protooncogene, c-erbB-2, is distinct from the c-erbB-1/epidermal growth factor-receptor gene and is amplified in a human salivary gland adenocarcinoma.

Kentaro Semba, Nobuyuki Kamata, K Toyoshima et al. · Proceedings of the National Academy of Sciences · 1985 · 606 citations · Full text

Engineering, Genetics, Salivary Gland +17

Expression of c-erbB-2 oncoprotein: a prognostic indicator in human breast cancer.

C Wright, Brian Angus, S Nicholson et al. · PubMed · 1989 · 587 citations

Gene Amplification, Breast Oncology, Earlier Relapse +19

HER-2/neu amplification predicts poor survival in node-positive breast cancer.

Åke Borg, Amol Tandon, Gary M. Clark et al. · PubMed · 1990 · 462 citations

Tumor Biology, Gene Amplification, Breast Oncology +12