A v-erbB-related protooncogene, c-erbB-2, is distinct from the c-erbB-1/epidermal growth factor-receptor gene and is amplified in a human salivary gland adenocarcinoma.

Kentaro Semba, Nobuyuki Kamata, K Toyoshima, +1

Proceedings of the National Academy of Sciences

EngineeringGeneticsSalivary GlandTumor BiologyReceptor Tyrosine Kinase +15

High incidence of amplification of the epidermal growth factor receptor gene in human squamous carcinoma cell lines.

Tadashi Yamamoto, Nobuyuki Kamata, H Kawano, +7

PubMed

Tumor BiologyMalignant DiseaseReceptor GeneMedicineCancer Cell Biology +10

Localization of a novel v-erbB-related gene, c-erbB-2, on human chromosome 17 and its amplification in a gastric cancer cell line.

S. Fukushige, Keiko Matsubara, Megumi Yoshida, +5

Molecular and Cellular Biology

Tumor BiologyRadiation OncologyChromatinOncogenic AgentMedicine +12

Correlation between long-term survival in breast cancer patients and amplification of two putative oncogene-coamplification units: hst-1/int-2 and c-erbB-2/ear-1.

Hitoshi Tsuda, S Hirohashi, Yukío Shimosato, +7

PubMed

Breast OncologyGeneticsPathologyLong-term SurvivalPutative Oncogene-coamplification Units +14

Avian sarcoma virus Y73 genome sequence and structural similarity of its transforming gene product to that of Rous sarcoma virus

N Kitamura, Atsunori Kitamura, K Toyoshima, +2

Nature

Gene ProductVirus StructureGeneticsMolecular BiologyVirology +8

The yes-related cellular gene lyn encodes a possible tyrosine kinase similar to p56lck.

Yuji Yamanashi, S. Fukushige, Kentaro Semba, +5

Molecular and Cellular Biology

GeneticsPossible Tyrosine KinaseMolecular GeneticsEpigeneticsCellular Physiology +18

yes-related protooncogene, syn, belongs to the protein-tyrosine kinase family.

Kentaro Semba, M Nishizawa, Noriyuki Miyajima, +6

Proceedings of the National Academy of Sciences

Systems BiologySignal TransductionProtein-tyrosine KinaseC-syn GeneReceptor Tyrosine Kinase +12

Phosphorylation of the retinoblastoma protein by cdk2.

Tetsu Akiyama, T Ohuchi, Satoshi Sumida, +2

Proceedings of the National Academy of Sciences

Signal TransductionCell RegulationCell DivisionReceptor Tyrosine KinaseImmunology +13

Characterization of Y73, an avian sarcoma virus: a unique transforming gene and its product, a phosphopolyprotein with protein kinase activity.

S Kawai, Minoru Yoshida, K Segawa, +3

Proceedings of the National Academy of Sciences

Viral ReplicationImmunologyPathologyViral Structural ProteinVirus Gene +14

The tumour suppressor gene product APC blocks cell cycle progression from G0/G1 to S phase.

Gyeong‐Hun Baeg, Akihiko Matsumine, Toshihiko Kuroda, +4

The EMBO Journal

Tumor BiologyCell RegulationCell DivisionMedicineCancer Cell Biology +9