Abnormal production of the tumor necrosis factor inhibitor etanercept and clinical efficacy of tumor in a patient with PAPA syndrome

The Inflammasome

Fabio Martinon, Kimberly Burns, Jürg Tschopp · Molecular Cell · 2002 · 6K citations · Full text

Etanercept in Children with Polyarticular Juvenile Rheumatoid Arthritis

Daniel J. Lovell, Edward H. Giannini, Andreas Reiff et al. · New England Journal of Medicine · 2000 · 1.3K citations · Full text

Medicine, Immunology, Pediatrics +7

Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway

Nitza G. Shoham, Michael Centola, Elizabeth Mansfield et al. · Proceedings of the National Academy of Sciences · 2003 · 489 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Mutations in CD2BP1 disrupt binding to PTP PEST and are responsible for PAPA syndrome, an autoinflammatory disorder

Carol A. Wise · Human Molecular Genetics · 2002 · 446 citations

Medicine, Genetics, Molecular Genetics +17

Targeted Disruption of Pyrin, the FMF Protein, Causes Heightened Sensitivity to Endotoxin and a Defect in Macrophage Apoptosis

Jae Jin Chae, Hirsh D. Komarow, Jun Cheng et al. · Molecular Cell · 2003 · 407 citations · Full text

Life Sciences, Cell Biology, Immunology +16