A Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene <i>BRCA1</i>

Yoshio Miki, Jeffrey Swensen, Donna Shattuck-Eidens, +42

Science

Breast OncologyEngineeringGeneticsBrca1 GeneTumor Biology +14

A System for Stable Expression of Short Interfering RNAs in Mammalian Cells

Thijn R. Brummelkamp, René Bernards, Reuven Agami

Science

Functional GenomicsPsuper VectorShort Interfering RnasGeneticsMedicine +13

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

Jamil Momand, Gerard P. Zambetti, David C. Olson, +2

Cell

Oncogenic AgentMedicineMolecular BiologyP53 ProteinP53-mediated Transactivation +7

<i>BRCA1</i> Mutations in Primary Breast and Ovarian Carcinomas

P. Andrew Futreal, Qingyun Liu, Donna Shattuck-Eidens, +24

Science

Nucleolar proteome dynamics

Jens Andersen, Yun Wah Lam, Anthony K. L. Leung, +4

Nature

ChromatinProtein FoldingMedicineNatural SciencesBiophysical Aspect +6

Directed Proteomic Analysis of the Human Nucleolus

Jens Andersen, Carol E. Lyon, Archa H. Fox, +5

Current Biology

Proteomic TechnologyChromatinMedicineNatural SciencesProteasome +5

Dynamic Changes of BRCA1 Subnuclear Location and Phosphorylation State Are Initiated by DNA Damage

Ralph Scully, Junjie Chen, Robert Ochs, +4

Cell

ChromatinGenome InstabilityDynamic ChangesDna DamageChromatin Remodeling +5

The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds

Sean V. Tavtigian, Jacques Simard, Johanna M. Rommens, +47

Nature Genetics

ChromatinCytogeneticsGenetic DisorderGeneticsComplete Brca2 Gene +6

Fine structural organization of the interphase nucleus in some mammalian cells

Ariane Monneron, W. Bernhard

Journal of Ultrastructure Research

ChromatinFine Structural OrganizationChromatin StructureCell DivisionNuclear Structure +13

BRCA1 physically associates with p53 and stimulates its transcriptional activity

Hongbing Zhang, Kumaravel Somasundaram, Yi Peng, +5

Oncogene

Transcriptional RegulationCell RegulationMedicineGeneticsTumor Suppressor +5