Concepedia

On-line screening of conformationally constrained nicotines and anabasines for agonist activity at the α3β4- and α4β2-nicotinic acetylcholine receptors using immobilized receptor-based liquid chromatographic stationary phases

Ruin Moaddel, Krzysztof Jóźwiak, Ryoji Yamaguchi, C COBELLO, Kevin Whittington, T. K. Sarkar, Shatarupa Basak, I.W. Wainer

Journal of Chromatography B · 2004 · 28 citations · 14 references

DOI

Concepts

References

14

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

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Neuronal Nicotinic Acetylcholine Receptors as Novel Drug Targets

G. Kenneth Lloyd, Michael Williams · Journal of Pharmacology and Experimental Therapeutics · 2000 · 312 citations

, , +17

Analysis of Mecamylamine Stereoisomers on Human Nicotinic Receptor Subtypes

Roger L. Papke, Paul R. Sanberg, R. Douglas Shytle · Journal of Pharmacology and Experimental Therapeutics · 2001 · 267 citations

, , +17

Rat α3/β4 Subtype of Neuronal Nicotinic Acetylcholine Receptor Stably Expressed in a Transfected Cell Line: Pharmacology of Ligand Binding and Function

Yingxian Xiao, Erin L. Meyer, J Thompson et al. · Molecular Pharmacology · 1998 · 249 citations · Full text

, , +17

Individual Changes in Clozapine Levels After Smoking Cessation: Results and a Predictive Model

Jonathan M. Meyer · Journal of Clinical Psychopharmacology · 2001 · 123 citations

, , +17