Level of retinoblastoma protein expression correlates with p16 (MTS-1/INK4A/CDKN2) status in bladder cancer

A comprehensive genetic map of the human genome based on 5,264 microsatellites

Colette Dib, Sabine Fauré, Cécile Fizames et al. · Nature · 1996 · 3K citations

Genetic Analysis, Haplotype Determination, Medicine +10

A Cell Cycle Regulator Potentially Involved in Genesis of Many Tumor Types

Alexander Kamb, Nelleke A. Gruis, Jane Weaver-Feldhaus et al. · Science · 1994 · 2.8K citations

5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

Adrian Merlo, James G. Herman, Li Mao et al. · Nature Medicine · 1995 · 2K citations

Tumor Biology, Transcriptional Regulation, Medicine +14

ARF Promotes MDM2 Degradation and Stabilizes p53: ARF-INK4a Locus Deletion Impairs Both the Rb and p53 Tumor Suppression Pathways

Yanping Zhang, Yue Xiong, Wendell G. Yarbrough · Cell · 1998 · 1.6K citations · Full text

Tumor Biology, Cell Regulation, Medicine +9

The Ink4a Tumor Suppressor Gene Product, p19Arf, Interacts with MDM2 and Neutralizes MDM2's Inhibition of p53

Jason H. Pomerantz, Nicole Schreiber‐Agus, Nanette J. Liégeois et al. · Cell · 1998 · 1.5K citations · Full text

Tumor Biology, Neutralizes Mdm2, Medicine +6