In a drug discrimination procedure isolation-reared rats generalize to lower doses of cocaine and amphetamine than rats reared in an enriched environment

Learning causes synaptogenesis, whereas motor activity causes angiogenesis, in cerebellar cortex of adult rats.

James Black, Kevin R. Isaacs, Brenda J. Anderson et al. · Proceedings of the National Academy of Sciences · 1990 · 1.2K citations · Full text

Motor Learning, Muscle Function, Developmental Cognitive Neuroscience +22

Dopamine Receptor Binding Enhancement Accompanies Lesion-Induced Behavioral Supersensitivity

Ian Creese, David R. Burt, Solomon H. Snyder · Science · 1977 · 714 citations

Behavioral Neuroscience, Neuroanatomy, Medicine +14

Enriched and impoverished environments: Effects on brain and behavior

Steven P. R. Rose · Neuropsychologia · 1990 · 289 citations

Impoverished Environments, Behavioral Sciences, Social Behavior +5

The effects of psychomotor stimulants on stereotypy and locomotor activity in socially-deprived and control rats

Barbara J. Sahakian, Trevor W. Robbins, Michael J. Morgan et al. · Brain Research · 1975 · 279 citations

Neuropsychology, Psychoactive Drug, Psychiatry +9

Cocaine self-administration in rats influenced by environmental conditions: implications for the etiology of drug abuse

Susan Schenk, Gary Lacelle, Kathleen M. Gorman et al. · Neuroscience Letters · 1987 · 207 citations

Substance Abuse, Behavioral Sciences, Substance Use +14