Helvetica Chimica Acta · 1958 · 91 citations · 13 references
Natural SciencesBiochemistryChemistryBioisosterismOrganic ChemistrySteroid BiochemistryBioinorganic ChemistryVitamin BiochemistryVitamin ChemistryCrystalline StructureIsoprenoidsUbiquinone BiosynthesisUbiquinone ChemistryVitamin Structure Elucidation
Abstract The isolation in pure form of the ubiquinone from pig heart is described. From 750 kg raw material 37 g of pure crystalline material could be obtained. Its structure has been established as that of a 2,3‐dimethoxy‐5‐methyl‐benzoquinone derivative with a vitamin‐K 2 ‐like isoprenoid side chain of 50 carbon atoms (I). It is proposed to name this compound ubiquinone(50).
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Isolation of a quinone from beef heart mitochondria
F.L. Crane, Youssef Hatefi, Robert L. Lester et al. · Biochimica et Biophysica Acta · 1957 · 583 citations
COENZYME Q. I. STRUCTURE STUDIES ON THE COENZYME Q GROUP
Donald E. Wolf, Carl H. Hoffman, Nelson R. Trenner et al. · Journal of the American Chemical Society · 1958 · 129 citations
Aspects of Vitamin a Deficiency in Rats
J. S. Lowe, R. A. Morton, R. G. Harrison · Nature · 1953 · 91 citations