RAM, a gene of yeast required for a functional modification of RAS proteins and for production of mating pheromone a-factor

Yeast transformation: a model system for the study of recombination.

Terry L. Orr‐Weaver, Jack W. Szostak, Rodney Rothstein · Proceedings of the National Academy of Sciences · 1981 · 1.5K citations

Chromatin, Genome Instability, Fungal Cell Biology +14

High-frequency transformation of yeast: autonomous replication of hybrid DNA molecules.

Kevin Struhl, Dan T. Stinchcomb, Stephen W. Scherer et al. · Proceedings of the National Academy of Sciences · 1979 · 1.5K citations · Full text

Engineering, Genetics, Y Vectors +17

Mechanism of activation of a human oncogene

Clifford J. Tabin, Scott M. Bradley, Cornelia I. Bargmann et al. · Nature · 1982 · 1.4K citations

Signal Transduction, Oncogenic Agent, Human Oncogene +4

A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene

E. Premkumar Reddy, Roberta K. Reynolds, Eugenio Santos et al. · Nature · 1982 · 1.4K citations

Tumor Biology, Urology, Somatic Variant +9

In yeast, RAS proteins are controlling elements of adenylate cyclase

Takashi Toda, Isao Uno, Tatsuo Ishikawa et al. · Cell · 1985 · 1.1K citations

Biochemistry, Natural Sciences, Molecular Biology +5