Assembly and extension of yeast artificial chromosomes to build up a large locus

Methods in Yeast Genetics

Heiner Jacob · Bioelectrochemistry and Bioenergetics · 1988 · 4.9K citations

Biology, Genetics, Yeast +4

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

Kirk R. Thomas, Mario R. Capecchi · Cell · 1987 · 2.4K citations

Embryonic Stem Cell, Induced Pluripotent Stem Cell, Developmental Biology +9

A positive selection for mutants lacking orotidine-5′-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance

Jef D. Boeke, Francois La Croute, Gerald R. Fink · Molecular and General Genetics MGG · 1984 · 2.4K citations

Orotidine-5′-phosphate Decarboxylase Activity, Cellular Enzymology, Biochemistry +7

Cloning of Large Segments of Exogenous DNA into Yeast by Means of Artificial Chromosome Vectors

David Burke, Georges F. Carle, Maynard V. Olson · Science · 1987 · 1.5K citations

Artificial Chromosome Vectors, Engineering, Exogenous Dna +22

Clustered arrangement of immunoglobulin λ constant region genes in man

Philip Hieter, Gregory Hollis, Stanley J. Korsmeyer et al. · Nature · 1981 · 369 citations

Histocompatibility, Immunogenetics, Clustered Arrangement +8