Concepedia

Concomitant inactivation of p53 and Chk2 in breast cancer

Alexandra Sullivan, Martin Yuille, Claire E. Repellin, Archana Reddy, Olivier Reelfs, Alexandra Bell, Barbara Dunne, Barry A. Gusterson, Peter Osin, Paul J. Farrell,

Oncogene · 2002 · 91 citations · 20 references

DOI

Concepts

References

20

DNA Damage-Induced Activation of p53 by the Checkpoint Kinase Chk2

Atsushi Hirao, Young‐Yun Kong, Shuhei Matsuoka et al. · Science · 2000 · 1.3K citations

Heterozygous Germ Line <i>hCHK2</i> Mutations in Li-Fraumeni Syndrome

Daphne W. Bell, Jennifer M. Varley, Tara E. Szydlo et al. · Science · 1999 · 899 citations

A "quickscore" method for immunohistochemical semiquantitation: validation for oestrogen receptor in breast carcinomas.

Simone Detre, G Saclani Jotti, Mitch Dowsett · Journal of Clinical Pathology · 1995 · 873 citations · Full text

Chk2/hCds1 functions as a DNA damage checkpoint in G<sub>1</sub>by stabilizing p53

Nabil Chehab, Asra Malikzay, Michael Appel et al. · Genes & Development · 2000 · 784 citations · Full text

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hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response

Jong‐Soo Lee, Kimberly M. Collins, Alexandra L. Brown et al. · Nature · 2000 · 528 citations

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