High-Fat-Diet-Induced Obesity and Heart Dysfunction Are Regulated by the TOR Pathway in Drosophila

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

Andrea H. Brand, Norbert Perrimon · Development · 1993 · 9.7K citations

Insulin signalling and the regulation of glucose and lipid metabolism

Alan R. Saltiel, C. Ronald Kahn · Nature · 2001 · 5.2K citations · Full text

Metabolic Syndrome, Insulin Signaling, Signal Transduction +13

Defective Lipolysis and Altered Energy Metabolism in Mice Lacking Adipose Triglyceride Lipase

Guenter Haemmerle, Achim Lass, Robert Zimmermann et al. · Science · 2006 · 1.4K citations · Full text

Metabolic Syndrome, Energy Homeostasis, Biochemistry +12

SREBP Activity Is Regulated by mTORC1 and Contributes to Akt-Dependent Cell Growth

Thomas Porstmann, Cláudio R. Santos, B Griffiths et al. · Cell Metabolism · 2008 · 1.4K citations · Full text

Influence of TOR kinase on lifespan in C. elegans

Tibor Vellai, Krisztina Takács‐Vellai, Yue Zhang et al. · Nature · 2003 · 1K citations · Full text

Lifespan Extension, Developmental Biology, Longevity +6