Concepedia

The ShcA adaptor activates AKT signaling to potentiate breast tumor angiogenesis by stimulating VEGF mRNA translation in a 4E-BP-dependent manner

Young Kyuen Im, Rachel La Selva, Valentina Gandin, Jacqueline R. Ha, Valérie Sabourin, Nahum Sonenberg, Tony Pawson, Ivan Topisirović, Josie Ursini‐Siegel

Oncogene · 2014 · 25 citations · 45 references

DOI

Concepts

References

45

Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease.

Chantale T. Guy, Robert D. Cardiff, William J. Muller · Molecular and Cellular Biology · 1992 · 1.5K citations · Full text

, , +17

A unifying model for mTORC1-mediated regulation of mRNA translation

Carson C. Thoreen, Lynne Chantranupong, Heather R. Keys et al. · Nature · 2012 · 1.5K citations · Full text

, , +16

The translational landscape of mTOR signalling steers cancer initiation and metastasis

Andrew C. Hsieh, Yi Liu, Merritt P. Edlind et al. · Nature · 2012 · 1.4K citations

, , +14

Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function

Arnim Pause, Graham J. Belsham, Anne‐Claude Gingras et al. · Nature · 1994 · 1.2K citations

, , +16

Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40

Emilie Vander Haar, Seong-il Lee, Sricharan Bandhakavi et al. · Nature Cell Biology · 2007 · 1.2K citations

, , +12