VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

Peter Carmeliet, Valérie Ferreira, Georg Breier et al. · Nature · 1996 · 4.1K citations

Life Sciences, Developmental Biology, Genetics +14

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

Fouad Shalaby, Janet Rossant, Terry P. Yamaguchi et al. · Nature · 1995 · 3.9K citations

Medicine, Cell Biology, Pathology +8

Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

Napoleone Ferrara, Karen Carver-Moore, Helen Chen et al. · Nature · 1996 · 3.7K citations · Full text

Life Sciences, Genetics, Molecular Genetics +11

Vascular Endothelial Growth Factor Regulates Endothelial Cell Survival through the Phosphatidylinositol 3′-Kinase/Akt Signal Transduction Pathway

Hans-Peter Gerber, Amy E. McMurtrey, Joe Kowalski et al. · Journal of Biological Chemistry · 1998 · 2K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Impaired recruitment of bone-marrow–derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth

David Lyden, Koichi Hattori, Sérgio Dias et al. · Nature Medicine · 2001 · 1.9K citations

Medicine, Cancer Biology, Oncology +16