Inositol 1,4,5-trisphosphate- and arachidonic acid-induced calcium mobilization in T and B lymphocytes

Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate

H. Streb, R.F. Irvine, Michael J. Berridge et al. · Nature · 1983 · 2.6K citations

Molecular Physiology, Signal Transduction, Biochemistry +11

Transmembrane signalling by the T cell antigen receptor. Perturbation of the T3-antigen receptor complex generates inositol phosphates and releases calcium ions from intracellular stores.

John B. Imboden, John D. Stobo · The Journal of Experimental Medicine · 1985 · 732 citations

T-regulatory Cell, Immunology, Ca2+ Ionophore +16

myo-Inositol 1,4,5-trisphosphate. A second messenger for the hormonal mobilization of intracellular Ca2+ in liver.

Suresh K. Joseph, Andrew P. Thomas, Rebecca J Williams et al. · Journal of Biological Chemistry · 1984 · 566 citations · Full text

Second Messenger, Hormonal Mobilization, Cellular Pharmacology +20

Inositol trisphosphate formation and calcium mobilization in Swiss 3T3 cells in response to platelet-derived growth factor

Michael J. Berridge, John P. Heslop, Robin F. Irvine et al. · Biochemical Journal · 1984 · 520 citations · Full text

Role of T3 surface molecules in human T-cell activation: T3-dependent activation results in an increase in cytoplasmic free calcium.

Anna Weiss, John B. Imboden, Dolores Shoback et al. · Proceedings of the National Academy of Sciences · 1984 · 447 citations · Full text

T-regulatory Cell, Immunology, Immune Regulation +21