Controlling epithelial sodium channels with light using photoswitchable amilorides

Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits

Cecilia M. Canessa, Laurent Schild, Gary Buell et al. · Nature · 1994 · 2K citations

Natural Sciences, Biochemistry, Biophysics +13

Structure of acid-sensing ion channel 1 at 1.9 Å resolution and low pH

J. Jasti, Hiroyasu Furukawa, Eric B. Gonzales et al. · Nature · 2007 · 1.1K citations

Natural Sciences, Biochemistry, Biophysics +15

Early death due to defective neonatal lung liquid clearance in αENaC-deficient mice

Edith Hümmler, Pierre Barker, John T. Gatzy et al. · Nature Genetics · 1996 · 878 citations · Full text

Medicine, Pediatrics, Neonatal Health +9

Mutations in subunits of the epithelial sodium channel cause salt wasting with hyperkalaemic acidosis, pseudohypoaldosteronism type 1

Su'e Chang, Stefan Gründer, Aaron Hanukoglu et al. · Nature Genetics · 1996 · 814 citations

Medicine, Molecular Genetics, Physiology +15

Light-activated ion channels for remote control of neuronal firing

Matthew R. Banghart, Katharine Borges, Ehud Y. Isacoff et al. · Nature Neuroscience · 2004 · 717 citations · Full text

Life Sciences, Neurobiology, Neuroscience +16