Multiple Novel Nonsynonymous CYP2B6 Gene Polymorphisms in Caucasians: Demonstration of Phenotypic Null Alleles

SIFT: predicting amino acid changes that affect protein function

P.C. Ng · Nucleic Acids Research · 2003 · 6.7K citations · Full text

Single Nucleotide Polymorphism, Genetics, Genetic Epidemiology +20

Human non-synonymous SNPs: server and survey

Vasily Ramensky · Nucleic Acids Research · 2002 · 2.3K citations · Full text

Bioinformatics, Human Non-synonymous Snps, Genome-wide Association Study +15

Improving the prediction of protein secondary structure in three and eight classes using recurrent neural networks and profiles

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Mammalian Microsomal Cytochrome P450 Monooxygenase

Pamela A. Williams, José Cosme, Vandana Sridhar et al. · Molecular Cell · 2000 · 689 citations · Full text

Biochemistry, Medicine, Biochemical Genetics +6

The Cytochrome P450 2B6 (CYP2B6) Is the Main Catalyst of Efavirenz Primary and Secondary Metabolism: Implication for HIV/AIDS Therapy and Utility of Efavirenz as a Substrate Marker of CYP2B6 Catalytic Activity

Bryan A. Ward, J. Christopher Gorski, David R. Jones et al. · Journal of Pharmacology and Experimental Therapeutics · 2003 · 591 citations