Synthesis of β,γ-unsaturated amino acids as potential catalytic irreversible enzyme inhibitors

4‐Amino‐hex‐5‐enoic Acid, a Selective Catalytic Inhibitor of 4‐Aminobutyric‐Acid Aminotransferase in Mammalian Brain

Bruce Lippert, Brian W. Metcalf, Michel J. Jung et al. · European Journal of Biochemistry · 1977 · 379 citations · Full text

Life Sciences, Biochemistry, Biocatalysis +15

Chemistry and Enzymology of <i>k</i> _cat Inhibitors

Robert R. Rando · Science · 1974 · 284 citations

Life Sciences, Biochemistry, Chemistry +10

Catalytic inhibition of γ-aminobutyric acid-α-ketoglutarate transaminase of bacterial origin by 4-aminohex-5-ynoic acid, a substrate analog

Michel J. Jung, Brian W. Metcalf · Biochemical and Biophysical Research Communications · 1975 · 136 citations

Life Sciences, Biochemistry, Microbiology +11

Applications of nuclear magnetic resonance spectroscopy in organic chemistry

L. H. Sutcliffe · Polymer · 1960 · 127 citations

Natural Sciences, Chemistry, Physics +11

Regiospecific 1,4 addition of a propargylic anion. A general synthon for 2-substituted propargylamines as potential catalytic irreversible enzyme inhibitors.

Brian W. Metcalf, Patrick Casara · Tetrahedron Letters · 1975 · 73 citations

Life Sciences, Chemistry, Medicinal Chemistry +13