The roles of CCR6 in migration of Th17 cells and regulation of effector T-cell balance in the gut

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

Estelle Bettelli, Yijun Carrier, Wenda Gao et al. · Nature · 2006 · 6.8K citations

Developmental Biology, Autoimmune Disease, Lymphocyte Development +13

The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells

Ivaylo I. Ivanov, Brent S. McKenzie, Liang Zhou et al. · Cell · 2006 · 5K citations · Full text

Inflammation, Cytokine, Lymphocyte Development +9

TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells

Marc Veldhoen, Richard J. Hocking, Christopher J. Atkins et al. · Immunity · 2006 · 3.6K citations · Full text

Inflammation, Cytokine, Lymphocyte Development +9

Transforming growth factor-β induces development of the TH17 lineage

Paul R. Mangan, Laurie E. Harrington, Darrell B. O’Quinn et al. · Nature · 2006 · 3K citations

Developmental Biology, Th17 Lineage, Cell Proliferation +3

A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-β– and retinoic acid–dependent mechanism

Janine L. Coombes, Karima R.R. Siddiqui, Carolina V. Arancibia-Cárcamo et al. · The Journal of Experimental Medicine · 2007 · 2.6K citations · Full text