Concepedia

A positive role for c-Abl in Atm and Atr activation in DNA damage response

X Wang, Li Zeng, J Wang, Jenny Chau, Keng Po Lai, Deyong Jia, Anuradha Poonepalli, M. Prakash Hande, H Liu, Guang He,

Cell Death and Differentiation · 2010 · 98 citations · 25 references

DOI

Concepts

References

25

Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma.

Yang Xu, Terry Ashley, E E Brainerd et al. · Genes & Development · 1996 · 838 citations · Full text

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Substrate Specificities and Identification of Putative Substrates of ATM Kinase Family Members

Seong‐Tae Kim, Dae‐Sik Lim, Christine E. Canman et al. · Journal of Biological Chemistry · 1999 · 814 citations · Full text

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p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage

Zhi-Min Yuan, Hisashi Shioya, Takatoshi Ishiko et al. · Nature · 1999 · 582 citations

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Interaction of c-Abl and p73α and their collaboration to induce apoptosis

Reuven Agami, Giovanni Blandino, Moshe Oren et al. · Nature · 1999 · 544 citations

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Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation

Rathinasamy Baskaran, Lauren D. Wood, Laura Whitaker et al. · Nature · 1997 · 542 citations

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