Concepedia

The syntheses of α-ketoamides via<sup>n</sup>Bu<sub>4</sub>NI-catalyzed multiple sp<sup>3</sup>C–H bond oxidation of ethylarenes and sequential coupling with dialkylformamides

Bingnan Du, Bo Jin, Peipei Sun

Organic & Biomolecular Chemistry · 2014 · 54 citations · 53 references

DOI

Concepts

Abstract

The (n)Bu4NI-catalyzed sequential C-O and C-N bond formation via multiple sp(3)C-H bond activation of ethylarenes, using N,N-dialkylformamide as the amino source, provided α-ketoamides with moderate yields.

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