Detection of single-strand breaks and formamidopyrimidine-DNA glycosylase-sensitive sites in DNA of cultured human fibroblasts

8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G-T and A-C substitutions.

Keith C. Cheng, D S Cahill, Hiroshi Kasai et al. · Journal of Biological Chemistry · 1992 · 1.8K citations · Full text

Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine.

César G. Fraga, Mark K. Shigenaga, J W Park et al. · Proceedings of the National Academy of Sciences · 1990 · 1.1K citations · Full text

Dna Damage, Aging, Genetics +20

Direct enzymic detection of endogenous oxidative base damage in human lymphocyte DNA

Andrew Collins, Susan J. Duthie, Victoria L. Dobson · Carcinogenesis · 1993 · 820 citations

Dna Damage, Lipid Peroxidation, Dna Analysis +20

Mechanistic studies of ionizing radiation and oxidative mutagenesis: genetic effects of a single 8-hydroxyguanine (7-hydro-8-oxoguanine) residue inserted at a unique site in a viral genome

Michael L. Wood, Miral Dizdaroglu, Ewa Gajewski et al. · Biochemistry · 1990 · 684 citations

8-oxoguanine (8-hydroxyguanine) DNA glycosylase and its substrate specificity.

Julia Tchou, Hiroshi Kasai, Shinya Shibutani et al. · Proceedings of the National Academy of Sciences · 1991 · 676 citations · Full text

Dna Glycosylase, Bioorganic Chemistry, Glycosylation +12