Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A‐ARF locus

A System for Stable Expression of Short Interfering RNAs in Mammalian Cells

Thijn R. Brummelkamp, René Bernards, Reuven Agami · Science · 2002 · 4.3K citations · Full text

Functional Genomics, Psuper Vector, Short Interfering Rnas +15

Role of Histone H3 Lysine 27 Methylation in Polycomb-Group Silencing

Ru Cao, Liangjun Wang, Hengbin Wang et al. · Science · 2002 · 3.7K citations

Histone Modifications, Epigenetic Change, Genetics +17

QUANTITATIVE STUDIES OF THE GROWTH OF MOUSE EMBRYO CELLS IN CULTURE AND THEIR DEVELOPMENT INTO ESTABLISHED LINES

George J. Todaro, Howard Green · The Journal of Cell Biology · 1963 · 2.7K citations · Full text

Cell Culture, Reproductive Biology, Cell Growth +17

Rb-Mediated Heterochromatin Formation and Silencing of E2F Target Genes during Cellular Senescence

Masashi Narita, Sabrina Nuñez, Édith Heard et al. · Cell · 2003 · 2.2K citations · Full text

Chromatin, Transcriptional Regulation, Developmental Biology +12

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

In-Kyung Park, Dalong Qian, Mark J. Kiel et al. · Nature · 2003 · 1.8K citations · Full text

Developmental Biology, Medicine, Stem Cell Mobilization +7