Concepedia

Inhibition of Platelet Functions and Thrombosis through Selective or Nonselective Inhibition of the Platelet P2 Receptors with Increasing Doses of NF449 [4,4′,4″,4″′-(Carbonylbis(imino-5,1,3-benzenetriylbis-(carbonylimino)))tetrakis-benzene-1,3-disulfonic Acid Octasodium Salt]

Béatrice Hechler, Stéphanie Magnenat, Maddalena L. Zighetti, Matthias U. Kassack, Heiko Ullmann, Jean‐Pierre Cazenave, Richard J. Evans, Marco Cattaneo, Christian Gachet

Journal of Pharmacology and Experimental Therapeutics · 2005 · 86 citations · 30 references

DOI

Concepts

References

30

A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE)

The Lancet · 1996 · 6.5K citations

, , +10

Molecular Basis for ADP-induced Platelet Activation

Jianguo Jin, James L. Daniel, Satya P. Kunapuli · Journal of Biological Chemistry · 1998 · 476 citations · Full text

, , +17

Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y1 receptor–null mice

Catherine Léon, Béatrice Hechler, Monique Freund et al. · Journal of Clinical Investigation · 1999 · 454 citations · Full text

, , +17

Decreased platelet aggregation, increased bleeding time and resistance to thromboembolism in P2Y1-deficient mice

Jean-Etienne Fabre, MyTrang Nguyen, Anne M. Latour et al. · Nature Medicine · 1999 · 440 citations

, , +16

ADP Receptors of Platelets and their Inhibition

Christian Gachet · Thrombosis and Haemostasis · 2001 · 416 citations

, , +17