Synthesis of primary amines via nucleophilic addition of organometallic reagents to aldimines on solid support

Structure-based, C2 symmetric inhibitors of HIV protease

Dale J. Kempf, Daniel W. Norbeck, LynnMarie Codacovi et al. · Journal of Medicinal Chemistry · 1990 · 211 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Preparation of primary amines and 2-azetidinones via N-(trimethylsilyl)imines

David J. Hart, Kenichi Kanai, Dudley G. Thomas et al. · The Journal of Organic Chemistry · 1983 · 183 citations

Natural Sciences, Chemistry, Medicinal Chemistry +6

Combinatorial Organic Synthesis of Highly Functionalized Pyrrolidines: Identification of a Potent Angiotensin Converting Enzyme Inhibitor from a Mercaptoacyl Proline Library

Martin M. Murphy, John R. Schullek, Eric M. Gordon et al. · Journal of the American Chemical Society · 1995 · 161 citations

Pharmacy, Chemistry, Medicinal Chemistry +10

Trimethylorthoformate: A mild and effective dehydrating reagent for solution and solid phase imine formation

Gary C. Look, Martin M. Murphy, David A. Campbell et al. · Tetrahedron Letters · 1995 · 154 citations

Pharmacy, Chemical Engineering, Chemistry +5

Protodetachable Arylsilane Polymer Linkages for Use in Solid Phase Organic Synthesis

Joseph A. Finkelstein, Balan Chenera, Daniel F. Veber · Journal of the American Chemical Society · 1995 · 115 citations

Natural Sciences, Chemistry, Organic Chemistry +8