Concepedia

The PG500 series: novel heparan sulfate mimetics as potent angiogenesis and heparanase inhibitors for cancer therapy

Keith Dredge, Edward Hammond, Keith Davis, C. P. Li, Ligong Liu, K. Johnstone, Pauline S. Handley, Norbert Wimmer, Thomas J. Gonda, Arvind Gautam,

Investigational New Drugs · 2009 · 118 citations · 11 references

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11

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

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Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis

Marta Pàez‐Ribes, Elizabeth Allen, James Hudock et al. · Cancer Cell · 2009 · 2.3K citations · Full text

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Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis

John M.L. Ebos, Christina R. Lee, William Cruz‐Muñoz et al. · Cancer Cell · 2009 · 1.7K citations · Full text

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Heparanase Induces Vascular Endothelial Growth Factor Expression: Correlation with p38 Phosphorylation Levels and Src Activation

Anna Zetser, Yulia Bashenko, Evgeny Edovitsky et al. · Cancer Research · 2006 · 231 citations · Full text

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Modulation of microvascular growth and morphogenesis by reconstituted basement membrane gel in three-dimensional cultures of rat aorta: A comparative study of angiogenesis in Matrigel, collagen, fibrin, and plasma clot

Roberto F. Nicosia, Antonio Ottinetti · In Vitro Cellular & Developmental Biology - Plant · 1990 · 222 citations

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