Keith Dredge

The anti-cancer agents lenalidomide and pomalidomide inhibit the proliferation and function of T regulatory cells

Christine Galustian, B Meyer, Marie‐Christine Labarthe et al. · Cancer Immunology Immunotherapy · 2008 · 387 citations · Full text

Medicine, Oncology, Pharmacology +13

Novel thalidomide analogues display anti-angiogenic activity independently of immunomodulatory effects

Keith Dredge, J B Marriott, Claire Macdonald et al. · British Journal of Cancer · 2002 · 292 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +8

Orally administered lenalidomide (CC-5013) is anti-angiogenic in vivo and inhibits endothelial cell migration and Akt phosphorylation in vitro

Keith Dredge, Rebecca Horsfall, Simon P. Robinson et al. · Microvascular Research · 2005 · 268 citations

Medicine, Oncology, Pharmacology +13

PG545, a dual heparanase and angiogenesis inhibitor, induces potent anti-tumour and anti-metastatic efficacy in preclinical models

Keith Dredge, Edward Hammond, Paul Handley et al. · British Journal of Cancer · 2011 · 165 citations · Full text

Medicine, Oncology, Pharmacology +17

Protective Antitumor Immunity Induced by a Costimulatory Thalidomide Analog in Conjunction with Whole Tumor Cell Vaccination Is Mediated by Increased Th1-Type Immunity

Keith Dredge, J B Marriott, Stephen Todryk et al. · The Journal of Immunology · 2002 · 165 citations · Full text

Life Sciences, Immunology, Oncology +17