Concepedia
Statistics
Publications
9
Citations
560
H-Index
Active since
1999
Affiliations
The University of Queensland(Current)
Griffith University
University of Newcastle Australia
Duke Medical Center
Paul Handley is an author at The University of Queensland specializing in glycobiology, medicine, and natural sciences.
Top concepts
MedicineGlycobiologyNatural SciencesBiochemistryPharmacologyChemical BiologyStructural BiologyMedicinal ChemistryChemistryBioanalysis
Publications per year
1999–2018
PG545, a dual heparanase and angiogenesis inhibitor, induces potent anti-tumour and anti-metastatic efficacy in preclinical models
Keith Dredge, Edward Hammond, Paul Handley et al. · British Journal of Cancer · 2011 · 165 citations · Full text
Discovery of PG545: A Highly Potent and Simultaneous Inhibitor of Angiogenesis, Tumor Growth, and Metastasis
Vito Ferro, Ligong Liu, Ken D. Johnstone et al. · Journal of Medicinal Chemistry · 2012 · 130 citations · Full text
Pharmaceutical Science, Glycobiology, Immunotherapeutics +22
A Phase I study of the novel immunomodulatory agent PG545 (pixatimod) in subjects with advanced solid tumours
Keith Dredge, Todd V. Brennan, Edward Hammond et al. · British Journal of Cancer · 2018 · 98 citations · Full text
Mechanisms of heparanase inhibition by the heparan sulfate mimetic PG545 and three structural analogues
Edward Hammond, Paul Handley, Keith Dredge et al. · FEBS Open Bio · 2013 · 59 citations · Full text
Structural Analogues, Tetrasaccharide Heparan Sulfate, Medicinal Chemistry +12
Immunomodulatory activities of pixatimod: emerging nonclinical and clinical data, and its potential utility in combination with PD-1 inhibitors
Edward Hammond, Nicole M. Haynes, Carleen Cullinane et al. · Journal for ImmunoTherapy of Cancer · 2018 · 49 citations · Full text
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