Organic & Biomolecular Chemistry · 2010 · 22 citations · 23 references
Natural SciencesChemistryMedicinal ChemistryDrug DiscoveryOrganic ChemistrySynthetic Medicinal ChemistryHeterocycle SynthesisHeterocyclic ChemistryHeterocyclic CompoundsMacrocycle SynthesisRetrosynthetic AnalysisAsymmetric Heterocycle SynthesisChiral Product SynthesisDiversity-oriented Total SynthesisEnantioselective Synthesis
A concise total synthesis of enantiopure circumdatins E, H and J has been developed using a reductive cyclization of chiral N-prolinoyl-2-nitrobenzamides to construct the core quinazolinone ring.
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