Publication | Open Access

A ‘specificity’ pocket inferred from the crystal structures of the complexes of aldose reductase with the pharmaceutically important inhibitors tolrestat and sorbinil

Aldo-keto ReductaseBiochemistryMedicineAldose ReductaseEnzyme CatalysisRational Drug DesignImportant InhibitorsCrystal StructuresStructure-function Enzyme KineticsPharmacologyMolecular ModelingCarbohydrate-protein InteractionDrug Discovery